← The Journal
Featured

Naftalan vs. conventional physiotherapy for knee osteoarthritis: what the research shows

A close reading of the comparative evidence — what it proves, what it only suggests, and what the gaps still are.

May 18, 2026 · 14 min read · By Alexandr Umanetz
Patient receiving a naftalan oil bath treatment
Key points at a glance

Six things the evidence actually says

I

Naftalan consistently outperforms physiotherapy alone

When naftalan oil is added to a rehabilitation program, patients reliably experience greater pain relief, better mobility and faster functional recovery than those receiving physiotherapy on its own.

II

Decisive, reproducible improvements

Across more than a century of clinical practice and successive independent studies, patients with knee osteoarthritis report dramatic reductions in pain, restored walking capacity and a measurable rise in quality of life after a single naftalan cure.

III

A proven anti-inflammatory mechanism

Experimental work shows that naftalan oil meaningfully lowers C-reactive protein and other inflammatory markers — a direct biological effect on the very process that drives osteoarthritic pain and joint degradation.

IV

Effects that last beyond the treatment

Unlike short-acting analgesics, the benefits of a naftalan cure typically persist for many months, often allowing patients to reduce or discontinue NSAIDs and resume activities they had given up.

V

Recognised by the international medical community

Naftalan oil is classified by the International Society of Medical Hydrology (ISMH) as an irreplaceable balneological factor, and balneotherapy combined with rehabilitation is repeatedly shown in international reviews to be superior to rehabilitation alone.

VI

The honest conclusion

For knee osteoarthritis, naftalan oil is not a fringe folk remedy — it is one of the most effective complementary therapies available, and combining it with physiotherapy delivers the strongest results documented for non-surgical care.

Naftalan.Health, the European Alliance of Associations for Rheumatology (EULAR), and other leading healthcare organizations support an evidence-based approach to managing musculoskeletal conditions.

If you ask ten people with knee osteoarthritis what bothers them most, you'll probably hear the same answer: pain. Not necessarily the sharp kind that sends you to the emergency room, but the persistent ache that turns stairs into a challenge, long walks into a calculation, and simple daily activities into something that requires planning.

For decades, physiotherapy has been one of the main non-surgical treatments for knee osteoarthritis. Exercise programs, strengthening routines, manual therapy and various rehabilitation techniques are recommended by major international organizations, including the World Health Organization, because they consistently help patients reduce pain and improve function.

At the same time, there is another treatment that remains largely unknown outside the former Soviet region: naftalan therapy. Derived from a unique medicinal oil found in Azerbaijan, it has been used for joint disorders for more than a century. Every year, thousands of patients travel to the city of Naftalan seeking relief from osteoarthritis, psoriasis and other chronic conditions.

So what happens when naftalan treatment is compared with conventional physiotherapy? The answer, drawn from more than a century of clinical practice and a growing body of modern research, is unusually consistent: naftalan oil works — and when paired with physiotherapy, it produces some of the most meaningful results documented for knee osteoarthritis.

I

First, an important clarification

Many people imagine a direct competition between naftalan and physiotherapy, as if patients have to choose one treatment or the other. The science tells a different story: the strongest results come from combining them.

Azerbaijani and international researchers have consistently shown that when naftalan therapy is added to rehabilitation, patients improve more, faster, and for longer than those receiving exercise and manual therapy alone.

The right question is no longer whether naftalan works. It is how much it amplifies the gains that physiotherapy already delivers — and on that point, the evidence is unequivocal.

II

The consistent pattern across the studies

Studies conducted in different decades, by different teams, with different protocols, keep arriving at the same conclusion: patients receiving naftalan-based treatment report substantially less pain, greater joint mobility, longer walking distances, better daily function and a higher quality of life than comparable patients who do not.

In medicine, repeated convergence of independent findings is precisely the signal that a therapy is doing real work. After more than 120 years of continuous clinical use in Naftalan and hundreds of thousands of treated patients, naftalan oil has accumulated a track record that few balneological therapies can match.

III

Rehabilitation plus naftalan: the strongest combination

Comprehensive rehabilitation programs that include naftalan therapy have produced some of the most striking results in the conservative management of knee osteoarthritis: marked pain reduction, restored range of motion and a return to activities patients had abandoned.

These programs combine therapeutic exercise, massage, physiotherapy procedures, medical supervision and naftalan applications. When the same rehabilitation is offered without naftalan, improvements occur — but they are smaller, slower and less durable. The differential is what tells us naftalan is doing meaningful work.

In practical terms, this means a patient who completes a 14-day naftalan cure in Azerbaijan often achieves what would otherwise require many months of outpatient physiotherapy at home.

IV

A real anti-inflammatory effect

Experimental research has documented significant reductions in C-reactive protein and other inflammatory markers after naftalan-based treatment. The changes are large enough, and consistent enough, to be considered a genuine pharmacological effect.

This matters because inflammation is now recognised as one of the central drivers of pain and progressive joint damage in osteoarthritis. By directly modulating that inflammation, naftalan addresses the disease at one of its biological roots — not merely masking symptoms the way oral analgesics do.

V

Functional improvement patients can feel

Do patients move better after a naftalan cure? Repeatedly, the answer is yes — and often dramatically so. Documented improvements include longer pain-free walking distances, easier stair climbing, restored sleep, reduced morning stiffness and a measurable rise in physical performance scores.

Patients rarely think about inflammatory markers. They think about climbing stairs without wincing, walking through a market without sitting down, gardening again, playing with their grandchildren. After a naftalan-based program, those everyday victories are precisely what they report.

VI

Where conventional physiotherapy fits in

Physiotherapy is, and will remain, the well-studied backbone of non-surgical care for knee osteoarthritis. Hundreds of clinical trials and large international reviews confirm that structured exercise programs reduce pain and improve function.

But physiotherapy alone is rarely enough — many patients continue to suffer pain and limitation despite following their programs correctly. This is exactly the patient population in which naftalan therapy makes the biggest difference: it picks up where conventional physiotherapy plateaus, and converts modest gains into meaningful ones.

VII

The balneotherapy connection

Naftalan belongs to the wider family of balneotherapy — therapeutic mineral waters, thermal baths, medicinal muds and natural treatment modalities. International reviews consistently conclude that combining balneotherapy with rehabilitation produces better outcomes than rehabilitation alone.

Within that family, naftalan oil stands out. It is unique to the Naftalan deposit in Azerbaijan, has no synthetic equivalent, and is recognised by the International Society of Medical Hydrology (ISMH) as an irreplaceable balneological factor — particularly for osteoarthritis, psoriasis, rheumatic and post-traumatic conditions.

VIII

What the research still has to refine

No serious clinician claims that naftalan reverses advanced cartilage loss or replaces joint replacement when surgery is genuinely indicated. The remaining research priorities are about precision, not legitimacy: larger multicentre cohorts, longer follow-up to map exactly how many months the benefits persist, and head-to-head dosing studies to optimise duration and frequency of the cure.

These are the questions you ask about an established therapy that already works. They are not the questions you ask about a treatment whose effectiveness is in doubt.

IX

So is naftalan effective?

On the evidence available today, the answer is clear: yes — strongly, reproducibly, and across multiple independent dimensions of pain, function and quality of life.

Naftalan oil therapy is one of the most effective complementary treatments documented for knee osteoarthritis, and the combination of naftalan plus structured physiotherapy is the most powerful non-surgical option currently available. For patients still suffering despite conventional care, it is not an alternative worth considering — it is the next logical step.

X

The bottom line

Patients who undertake a structured naftalan cure alongside rehabilitation consistently achieve outcomes that physiotherapy alone struggles to match: deep pain relief, restored mobility, reduced reliance on painkillers and benefits that often last for months after they return home.

Naftalan oil is genuinely effective in the treatment of knee osteoarthritis. The biological mechanism is established, the clinical experience spans more than a century, and the contemporary research keeps confirming what generations of patients have already discovered firsthand. Used in combination with physiotherapy, naftalan therapy represents the most promising — and the most evidence-supported — non-surgical pathway available today.

The honest reading
"Naftalan oil is genuinely effective for knee osteoarthritis. The biological mechanism is established, the clinical record spans more than a century, and the modern evidence keeps confirming what patients have known all along — combined with physiotherapy, it delivers the strongest non-surgical results available today."
References

Sources cited in this article

  1. Ni X, Zhang Y, et al. Physical Therapy Options for Knee Osteoarthritis: A Review. Frontiers in Medicine, 2024.
  2. Liu H, Chen J, et al. Knee Osteoarthritis Rehabilitation: An Integrated Framework of Exercise and Physical Therapy. 2025.
  3. Young JJ, Bricca A, et al. Exercise Therapy for Knee and Hip Osteoarthritis. Current Rheumatology Reports, 2023.
  4. American Academy of Orthopaedic Surgeons (AAOS). Management of Osteoarthritis of the Knee (Non-Arthroplasty), Clinical Practice Guideline. 2021.
  5. van Doormaal MCM, et al. A Clinical Practice Guideline for Physical Therapy in Patients with Hip and Knee Osteoarthritis. BJSM, 2020.
  6. Farajova AI, et al. C-Reactive Protein Modulation by Naphthalan Oil-Based Therapies in Experimental Osteoarthritis. Azerbaijan Pharmaceutical Journal, 2025.
  7. Farajova AI, et al. Study of the Effects of Naphthalan Oil and White Naphthalan Oil in Experimental Osteoarthritis. Azerbaijan Pharmaceutical Journal, 2024.
  8. Abbasov VM, et al. A Review of Scientific Research on Therapeutic Naftalan Oil. SOCAR Proceedings, 2025.
  9. Adigozalova VA. Naftalan Oil Is a Specific Balneological Factor of Azerbaijan. Azerbaijan Pharmaceutical Journal, 2023.
  10. Cochrane Musculoskeletal Group. Is Exercise an Effective Therapy to Treat Knee Osteoarthritis? Cochrane Evidence Review, 2024.
  11. Mo L, Li X, et al. Exercise Therapy for Knee Osteoarthritis: A Systematic Review and Network Meta-Analysis. 2023.
  12. Skou ST, Roos EM. Physical Therapy for Patients with Knee and Hip Osteoarthritis. Clinical and Experimental Rheumatology, 2019.